The number of individuals living with dementia is on the rise. By 2050, it鈥檚 expected that nearly 14 million Americans will be diagnosed with Alzheimer鈥檚 disease, up from 5.8 million today, . Experts around the globe are working to find a cure 鈥� including some in the D.C. area.
Researchers at are looking for individuals ages 60 to 75 that have not been diagnosed with any memory impairment, but do have a family history of Alzheimer’s disease, to enroll in a five- to eight-year clinical trial to test the effectiveness of a medication that may delay or prevent the symptoms of Alzheimer鈥檚 disease.
Dr. Thomas Obisesan, professor of medicine at Howard University Hospital, said it鈥檚 important to study treatments in those who don鈥檛 display symptoms of dementia because 鈥渨e now know that the disease begins about 15 to 20 years before the appearance of clinical symptoms.鈥�
鈥淭his presents an immense opportunity to begin to find ways to delay or prevent the appearance of clinical symptoms. Because once the disease is full blown, it鈥檚 far much more challenging to alter the trajectory or the course of the disease,鈥� Obisesan said.
Individuals interested in enrolling in the voluntary prevention initiative, called , will be tested for the gene APOE4, which can increase one鈥檚 risk for developing Alzheimer鈥檚. Those who test positive will be given either a placebo or the investigational treatment, which aims to prevent the build up of amyloid-尾 protein plaques in the brain 鈥� a protein present in patients with Alzheimer鈥檚. Research is ongoing to better understand how and when these plaques influence Alzheimer鈥檚 disease, according to the .
More information on how to enroll in the Howard University Hospital trial, as well as details on qualifications and the treatment being tested, is on Generation Program鈥檚 website or by calling 1-866-244-8907. is another resource where individuals can learn more about Alzheimer鈥檚 treatment and prevention trials going on around the country.
鈥淲e need people to participate in these clinical trials. It is not possible for clinician scientists to do this all by themselves,鈥� Obisesan said.
鈥淭hey need the cooperation of the community, and collectively working together we can make progress on conquering this devastating disease.鈥�
